Skip to main content

Protective Effect of Boswellic Resin

Nowadays, because of the industrialization, a lot of contaminant were available ; the consequences of this availability are apparition of diseases including neurodegeneration.

Neurodegenerative diseases of the human brain comprise a variety of disorders that affect an increasing percentage of the population. This study is based on the effect of the Boswellic resin, which is from a medicinal plant and known for its antioxidant effects on nerve cell damage.

The objective of this work was to evaluate the in vitro and in vivo effects of the Boswellic resin on anticholinesterase activity and Alzheimer’s disease (AD) induced by D-galactose and aluminum tetrachloride in Swiss mice.

(Experimental study in Mice)

Chemical composition of the resin essential oil was identified by the CG-MS analysis. The antioxidant activity was also assessed by the DMPD and metal chelation methods. In order to understand the mechanism of memory improvement, the acetylcholinesterase, AChE, and butyrylcholinesterase, BChE, inhibitory assays were performed. In vivo part of the study was achieved on Swiss mice divided into four groups: control, AD model, treated AD, and treated control group.

The identification of chemical composition by CG-MS reach the 89.67% of the total extract compounds presented some very important molecules (p-Cymene, n-Octyl acetate, α-Pinene…). The present study proves that Boswellic resin improves memory and learning in treated Alzheimer’s group, modulates the oxidative stress and be involved in the protective effect against amyloid deposition and neurodegeneration, and stimulates the immune system in mice’s brain

Leave a comment

You are commenting as guest. Optional login below.

Breaking news

Harvest jebel akhdar roses in oman

20 June 2022
At dawn, after the first morning prayer, the residents join the rose gardens. The harvest, which begins in spring, at the end of March, beginning o...

Frankincense and breast cancer

04 October 2022
Use of an extract of the ancient perfume frankincense — the hardened resin from trees of the Boswellia genus — decreased breast cancer cell prolife...

Preservation & royal perfume

10 October 2022
Use of an extract of the ancient perfume frankincense — the hardened resin from trees of the Boswellia genus — Muscat: The Ministry of Heritage and...
Incense burner from the Sultanate of Oman

The land of Frankincense

Oman natural frankincense

© 2022 All rights reserved.